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Evidence-graded supplement guides

Supplements that actually work, scored honestly.

Every guide on Health Britannica is graded on six metrics: efficacy, safety, dose accuracy, cost, interactions, and quality. We cite the research, name the brands worth buying, and tell you what the studies don't yet support. Free, no email required.

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30+
Evidence-graded guides
stacks, roundups, single-supplement deep dives
6
Scoring dimensions
efficacy, safety, dose, cost, interactions, quality
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Supplement Evidence Dashboard
PubMed study counts, proven vs. unproven claims, dose ranges, and interactions for 50+ supplements. The honest-grade reference we built so you don't have to dig through PubMed yourself.
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Curated stacks

Complete supplement protocols organized by goal. Each includes top product picks, synergy maps, timing schedules, and daily cost. Start with the Foundation Stack if you're new.

Stack guide
The Foundation Stack: 5 supplements everyone should take first
Magnesium, D3+K2, omega-3, creatine, multivitamin. The base every other stack builds on.
Stack guide
The Cognitive Stack: best nootropics for focus & memory
Lion's Mane, Alpha-GPC, L-Theanine, Bacopa, Citicoline. Three synergy protocols.
Stack guide
The Athlete Stack: strength, endurance & recovery
Protein, beta-alanine, citrulline, ashwagandha. Muscle, endurance, and recovery protocols.

Top product roundups

Lab-tested rankings for the most-asked supplements. Each pick includes brand, third-party testing certification, dose accuracy, and cost-per-serving.

Roundup
Best magnesium supplements in 2026: 15 brands tested & ranked
Glycinate, citrate, threonate, malate. Bioavailability, dose accuracy, third-party testing.
Roundup
Best creatine supplements in 2026: 10 brands lab-tested
Monohydrate vs HCl, micronized vs standard. Purity, mesh size, dose accuracy.
Roundup
Best ashwagandha in 2026: KSM-66 vs Sensoril vs generic
Withanolide content, root vs leaf extract, third-party verified brands.
Roundup
Best collagen supplements in 2026: types, brands & what works
Type I vs II vs III, hydrolyzed peptides, source variation, dose ranges.
Roundup
Best greens powders in 2026: AG1 vs alternatives
Ingredient density, blend transparency, real cost-per-serving math.
Roundup
Best mushroom supplements in 2026: Lion's Mane, Reishi, Cordyceps
Fruiting body vs mycelium, beta-glucan content, hot-water extracted brands.

Single-supplement deep dives

Mechanism of action, dose response curves, study saturation, brand quality, who it's actually for, and who should avoid it.

Deep dive
Ashwagandha KSM-66: benefits, safety, dosage
Cortisol reduction, sleep impact, testosterone evidence quality, dose-response curve.
Deep dive
Berberine: benefits, dosage, GLP-1 connection & safety
Glucose regulation evidence, "nature's Ozempic" claim audit, drug interactions.
Deep dive
Best nootropic supplements & pre-built stacks 2026
Single ingredients vs pre-made stacks, evidence-graded recommendations.
Browse all 30+ guides →

Our methodology

The 6-metric evidence scoring system

Every supplement guide on Health Britannica is scored on six independent dimensions. We cite the research that backs each score. When the research is thin or contradictory, we say so explicitly.

01
Efficacy
Randomized trial evidence quality + effect size
02
Safety
Side effect profile + long-term tolerability
03
Dose
Studied dose vs typical product label dose
04
Cost
Cost per studied dose, not per serving
05
Interactions
Known drug-drug and supplement-supplement interactions
06
Quality
Third-party testing, brand reputation, manufacturing

Read our editorial standards and affiliate disclosure for how we keep these scores honest.

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